alphagenome-variant-impact-score

alphagenome-variant-impact-score is a Bioinformatics & life sciences skill for AI agents, published by google-deepmind in the science-skills repository on GitHub. Skillspace rates alphagenome-variant-impact-score F (53/100) and it passed the safety scan; the rating is based on static analysis only.

Score, annotate, and analyze the functional impact of genetic variants using AlphaGenome Variant Impact (AVI) scores. Query variants in chr:pos:ref>alt format, annotate VCF/tabular callsets, perform saturation mutagenesis window scans (1-based closed chr:start-end), and extract GENCODE v46 GTF gene/exon/junction coordinates all via the AlphaGenome Atlas API.

Grade
F
Quality
53 / 100
Safety
Passed
GitHub stars
3,020

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

View source on GitHubgoogle-deepmind/science-skills

Our review

Architecture
80 / 100
Maturity
Basic: a single SKILL.md
Security scan
Low-risk patterns
License
Not declared. Check the repository before reusing it.

What the scanner flagged

  • mentions secrets in text

Not checked yet

  • Category is a classifier prediction; no model has read this skill yet
  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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