alterlab-cbioportal

alterlab-cbioportal is a Bioinformatics & life sciences skill for AI agents, published by AlterLab-IEU in the AlterLab-Academic-Skills repository on GitHub. Skillspace rates alterlab-cbioportal B (83/100) and it passed the safety scan; the rating is based on static analysis only.

Query cBioPortal via its keyless REST API for cancer genomics across TCGA, GENIE, MSK-IMPACT and hundreds of studies — somatic mutations, copy-number alterations (GISTIC), mRNA/protein expression, structural variants, and patient-level clinical/survival data. Use when asked how often a gene is mutated/amplified/deleted in a tumor type, to profile oncogenes or tumor suppressors across cancers (pan-cancer alteration frequency), to pull patient-level mutations joined to OS/clinical outcomes, or to validate a cancer target from cohort genomics. For germline variant pathogenicity use alterlab-clinvar; for mutational-signature (SBS) decomposition use alterlab-cosmic; for CRISPR/RNAi gene-dependency use alterlab-depmap; for aggregated target-disease evidence use alterlab-opentargets. Part of the AlterLab Academic Skills suite.

Grade
B
Quality
83 / 100
Safety
Passed
GitHub stars
43

Unproven: rated by static analysis only, not yet compared head-to-head.

Our two independent classifiers differ on this skill's category, so treat the placement as provisional.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
100 / 100
Maturity
Packaged: licensed, with a version or references
Security scan
Low-risk patterns
License
MIT
Adoption
Adopted by 0 other repositories, in 0 collections

What the scanner flagged

  • over-broad allowed-tools ('*')

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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