antibody-engineering

antibody-engineering is a Bioinformatics & life sciences skill for AI agents, published by K-Dense-AI in the drug-discovery-agent-skills repository on GitHub. Skillspace rates antibody-engineering C (77/100) and it passed the safety scan; the rating is based on static analysis only.

Number antibody variable domains, annotate CDRs, and assess developability from sequence. Use this skill to apply IMGT, Kabat, Chothia, Martin, or AHo numbering with ANARCI, delimit CDRs and framework regions, scan for chemical liabilities (N-glycosylation sequons, deamidation NG, isomerisation DG, oxidation, unpaired cysteine, fragmentation), compute pI, net charge, extinction coefficient and hydrophobicity, and plan humanisation by CDR grafting. Also trigger on antibody, nanobody, VHH, scFv, Fab, CDR, framework, ANARCI, abnumber, IgBLAST, OAS, SAbDab, humanization, Vernier residues, or developability.

Grade
C
Quality
77 / 100
Safety
Passed
GitHub stars
28

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
94 / 100
Maturity
Packaged: licensed, with a version or references
Security scan
No issues found
License
Not declared. Check the repository before reusing it.

Not checked yet

  • Category is a classifier prediction; no model has read this skill yet
  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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