bio-comparative-genomics-pangenome-analysis

bio-comparative-genomics-pangenome-analysis is a Bioinformatics & life sciences skill for AI agents, published by BioTender-max in the awesome-bio-agent-skills repository on GitHub. Skillspace rates bio-comparative-genomics-pangenome-analysis C (79/100) and it passed the safety scan; the rating is based on static analysis only.

Build and analyze pangenomes for prokaryotes (Panaroo, PPanGGOLiN, PEPPAN, GET_HOMOLOGUES, anvi'o pangenomics) and eukaryotes (Minigraph-Cactus, PGGB, vg pangenome graphs). Implement Tettelin core/accessory/cloud genome decomposition (Tettelin 2005), Heap's law open/closed pangenome modeling, gene presence/absence GWAS (Scoary, pyseer), pangenome graph variant calling (vg, PanGenie), and structural-variation graph indexing. Use when assembling species- or genus-level pan-gene catalogs, separating core from accessory/shell/cloud genes, testing gene-content associations with phenotypes, building pangenome graphs from haplotype-resolved assemblies, calling SVs from pangenome graphs, or selecting between bacterial-pangenome and eukaryotic-pangenome workflows.

Grade
C
Quality
79 / 100
Safety
Passed
GitHub stars
115

Unproven: rated by static analysis only, not yet compared head-to-head.

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View source on GitHubBioTender-max/awesome-bio-agent-skills

Our review

Architecture
97 / 100
Maturity
Structured: ships references or scripts
Security scan
No issues found
License
Not declared. Check the repository before reusing it.
Adoption
Adopted by 0 other repositories, in 2 collections

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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