boltz

boltz is a Bioinformatics & life sciences skill for AI agents, published by aipoch in the open-science repository on GitHub. Skillspace rates boltz D (64/100) and it passed the safety scan; the rating is based on static analysis only.

Structure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. 2025, github.com/jwohlwend/boltz). Reach for this skill to validate designed binders against a target, to co-fold a protein with a SMILES or CCD ligand, or to get an open-source AlphaFold3 alternative with optional binding-affinity prediction.

Grade
D
Quality
64 / 100
Safety
Passed
GitHub stars
4,174

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
82 / 100
Maturity
Basic: a single SKILL.md
Security scan
No issues found
License
Not declared. Check the repository before reusing it.

Not checked yet

  • Category is a classifier prediction; no model has read this skill yet
  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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