complexa-design
complexa-design is a Bioinformatics & life sciences skill for AI agents, published by NVIDIA-BioNeMo in the bionemo-agent-toolkit repository on GitHub. Skillspace rates complexa-design F (45/100) and the safety scan rated it risky; the rating is based on static analysis only.
Risky. This skill has patterns associated with unsafe behaviour. Read the source carefully before running it.
End-to-end Proteina-Complexa design pipeline driver. Reach for this skill whenever the user wants to "design a binder", "design binders for X", "run complexa design", "de novo binder", "PDL1 binder", "TrkA binder", "design proteins for target", "protein binder design", "ligand binder", "design a small-molecule binder", "ATP-binding protein", "AME motif scaffolding", "scaffold a motif near a ligand", "motif + ligand design", "enzyme scaffolding", "flow matching protein design", "beam-search binder", "FK steering", "MCTS protein design", "refold with AF2", "refold with RF3", "refold with ESMFold", or wants success rates, interface pAE, scRMSD, or FoldSeek diversity from a single command. This is the scientific anchor of the skill set: it drives `complexa design <pipeline>` from target picking to manifest emission and tells the user how many designs passed.
- Grade
- F
- Quality
- 45 / 100
- Safety
- Risky
- GitHub stars
- 371
Unproven: rated by static analysis only, not yet compared head-to-head.
Our two independent classifiers differ on this skill's category, so treat the placement as provisional.
This rating describes the version of the repository we crawled; it may have changed since.
Our review
- Architecture
- 78 / 100
- Maturity
- Structured: ships references or scripts
- Security scan
- High-risk patterns
- License
- Not declared. Check the repository before reusing it.
- Adoption
- Adopted by 0 other repositories, in 1 collections
What the scanner flagged
- dynamic code execution (eval/exec)
Not checked yet
- Category is a classifier prediction; no model has read this skill yet
- Not judged on the rubric yet (not a contender in its category)
- No blind task eval yet
- Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
- Sibling files (scripts, references) not fetched; security scan covers SKILL.md only
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