foldseek

foldseek is a Bioinformatics & life sciences skill for AI agents, published by adaptyvbio in the protein-design-skills repository on GitHub. Skillspace rates foldseek F (45/100) and the safety scan rated it risky; the rating is based on static analysis only.

Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.

Grade
F
Quality
45 / 100
Safety
Risky
GitHub stars
147

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since.

Our review

Architecture
84 / 100
Maturity
Basic: a single SKILL.md
Security scan
High-risk patterns
License
MIT
Adoption
Adopted by 0 other repositories, in 0 collections

What the scanner flagged

  • executes shell/subprocess

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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