hic-aggregation

hic-aggregation is a Bioinformatics & life sciences skill for AI agents, published by ammawla in the encode-toolkit repository on GitHub. Skillspace rates hic-aggregation C (75/100) and it passed the safety scan; the rating is based on static analysis only.

Build comprehensive chromatin contact maps by aggregating Hi-C loop calls (BEDPE) across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "what regions are in 3D contact in my tissue?" by creating a union catalog of chromatin loops. Handles resolution-aware anchor matching, cross-lab variation, and Hi-C-specific quality metrics.

Grade
C
Quality
75 / 100
Safety
Passed
GitHub stars
37

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
90 / 100
Maturity
Structured: ships references or scripts
Security scan
No issues found
License
AGPL-3.0
Adoption
Adopted by 0 other repositories, in 1 collections

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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