ld-1000g-region-compute

ld-1000g-region-compute is a Bioinformatics & life sciences skill for AI agents, published by ClawBio in the ClawBio repository on GitHub. Skillspace rates ld-1000g-region-compute C (78/100) and it passed the safety scan; the rating is based on static analysis only.

Compute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified. Use when an agent needs LD coloring for a regional plot or LD pruning around a candidate causal variant. Single client (on-demand region fetch from EBI 1000G FTP); no multi-GB cold-start.

Grade
C
Quality
78 / 100
Safety
Passed
GitHub stars
1,039

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
84 / 100
Maturity
Packaged: licensed, with a version or references
Security scan
No issues found
License
MIT
Adoption
Adopted by 0 other repositories, in 2 collections

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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