methylation-aggregation
methylation-aggregation is a Bioinformatics & life sciences skill for AI agents, published by ammawla in the encode-toolkit repository on GitHub. Skillspace rates methylation-aggregation C (75/100) and it passed the safety scan; the rating is based on static analysis only.
Build comprehensive DNA methylation maps by aggregating WGBS (Whole Genome Bisulfite Sequencing) data across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "where is DNA methylated/unmethylated in my tissue?" by combining per-CpG methylation data into tissue-level methylation profiles. Handles coverage filtering, identifies hypomethylated regions (HMRs) and partially methylated domains (PMDs), and manages cross-lab variation.
- Grade
- C
- Quality
- 75 / 100
- Safety
- Passed
- GitHub stars
- 37
Unproven: rated by static analysis only, not yet compared head-to-head.
This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.
Our review
- Architecture
- 90 / 100
- Maturity
- Structured: ships references or scripts
- Security scan
- No issues found
- License
- AGPL-3.0
- Adoption
- Adopted by 0 other repositories, in 1 collections
Not checked yet
- Not judged on the rubric yet (not a contender in its category)
- No blind task eval yet
- Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
- Sibling files (scripts, references) not fetched; security scan covers SKILL.md only
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