proteinmpnn
proteinmpnn is a Bioinformatics & life sciences skill for AI agents, published by adaptyvbio in the protein-design-skills repository on GitHub. Skillspace rates proteinmpnn C (71/100) and it passed the safety scan; the rating is based on static analysis only.
Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.
- Grade
- C
- Quality
- 71 / 100
- Safety
- Passed
- GitHub stars
- 147
Unproven: rated by static analysis only, not yet compared head-to-head.
Not launch-quality. It is graded C with a clean safety verdict, but our quality filters exclude it: it is a near-duplicate variant of another skill. So it is not in our launch-quality set, the skills our MCP server searches and recommends. How launch-quality is decided
This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.
Our review
- Architecture
- 82 / 100
- Maturity
- Packaged: licensed, with a version or references
- Security scan
- No issues found
- License
- MIT
- Adoption
- Adopted by 0 other repositories, in 0 collections
Not checked yet
- Category is a classifier prediction; no model has read this skill yet
- Not judged on the rubric yet (not a contender in its category)
- No blind task eval yet
- Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
- Sibling files (scripts, references) not fetched; security scan covers SKILL.md only
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