tooluniverse-cancer-variant-interpretation

tooluniverse-cancer-variant-interpretation is a Clinical knowledge & decision support skill for AI agents, published by FreedomIntelligence in the OpenClaw-Medical-Skills repository on GitHub. Skillspace rates tooluniverse-cancer-variant-interpretation C (70/100) and it passed the safety scan; the rating is based on static analysis only.

Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.

Grade
C
Quality
70 / 100
Safety
Passed
GitHub stars
2,848

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
80 / 100
Maturity
Structured: ships references or scripts
Security scan
No issues found
License
Not declared. Check the repository before reusing it.
Adoption
Adopted by 3 other repositories, in 13 collections
Scope
Vendor-specific: built around one product. Built on ToolUniverse tools over CIViC, cBioPortal, OpenTargets APIs

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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