tooluniverse-rnaseq-deseq2

tooluniverse-rnaseq-deseq2 is a Bioinformatics & life sciences skill for AI agents, published by FreedomIntelligence in the OpenClaw-Medical-Skills repository on GitHub. Skillspace rates tooluniverse-rnaseq-deseq2 C (74/100) and it passed the safety scan; the rating is based on static analysis only.

Production-ready RNA-seq differential expression analysis using PyDESeq2. Performs DESeq2 normalization, dispersion estimation, Wald testing, LFC shrinkage, and result filtering. Handles multi-factor designs, multiple contrasts, batch effects, and integrates with gene enrichment (gseapy) and ToolUniverse annotation tools (UniProt, Ensembl, OpenTargets). Supports CSV/TSV/H5AD input formats and any organism. Use when analyzing RNA-seq count matrices, identifying DEGs, performing differential expression with statistical rigor, or answering questions about gene expression changes.

Grade
C
Quality
74 / 100
Safety
Passed
GitHub stars
2,848

Unproven: rated by static analysis only, not yet compared head-to-head.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
88 / 100
Maturity
Structured: ships references or scripts
Security scan
No issues found
License
Not declared. Check the repository before reusing it.
Adoption
Adopted by 3 other repositories, in 13 collections
Scope
Vendor-specific: built around one product. PyDESeq2 and ToolUniverse public libraries workflow

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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