tooluniverse-single-cell

tooluniverse-single-cell is a Bioinformatics & life sciences skill for AI agents, published by FreedomIntelligence in the OpenClaw-Medical-Skills repository on GitHub. Skillspace rates tooluniverse-single-cell C (71/100) and it passed the safety scan; the rating is based on static analysis only.

Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering, differential expression (Wilcoxon, t-test, DESeq2), cell type annotation, per-cell-type statistical analysis, gene-expression correlation, batch correction (Harmony), trajectory inference, and cell-cell communication analysis. NEW: Analyzes ligand-receptor interactions between cell types using OmniPath (CellPhoneDB, CellChatDB), scores communication strength, identifies signaling cascades, and handles multi-subunit receptor complexes. Integrates with ToolUniverse gene annotation tools (HPA, Ensembl, MyGene, UniProt) and enrichment tools (gseapy, PANTHER, STRING). Supports h5ad, 10X, CSV/TSV count matrices, and pre-annotated datasets. Use when analyzing single-cell RNA-seq data, studying cell-cell interactions, performing cell type differential expression, computing gene-expression correlations by cell type, analyzing…

Grade
C
Quality
71 / 100
Safety
Passed
GitHub stars
2,848

Unproven: rated by static analysis only, not yet compared head-to-head.

Not launch-quality. It is graded C with a clean safety verdict, but our quality filters exclude it: it is a near-duplicate variant of another skill. So it is not in our launch-quality set, the skills our MCP server searches and recommends. How launch-quality is decided

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
83 / 100
Maturity
Structured: ships references or scripts
Security scan
No issues found
License
Not declared. Check the repository before reusing it.
Adoption
Adopted by 3 other repositories, in 11 collections
Scope
Vendor-specific: built around one product. scanpy, anndata, ToolUniverse public library workflows

Not checked yet

  • Category is a classifier prediction; no model has read this skill yet
  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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