ukb-ppp-region-fetch

ukb-ppp-region-fetch is a Bioinformatics & life sciences skill for AI agents, published by ClawBio in the ClawBio repository on GitHub. Skillspace rates ukb-ppp-region-fetch C (74/100) and it passed the safety scan; the rating is based on static analysis only.

Fetch a regional slice of plasma pQTL summary statistics from the UK Biobank Pharma Proteomics Project (UKB-PPP; Sun 2023 Nature) for a specific (protein, ancestry) measurement. Use when an agent needs per-variant beta / SE / p-value around a coloc-lead variant for downstream colocalisation, Mendelian randomisation, or regional plotting against a pQTL exposure. The canonical use case is the cis-window around the protein's coding gene TSS, but UKB-PPP releases full-genome summary stats per protein so any GRCh38 window (including trans loci) is supported when the user supplies an explicit (chromosome, start_bp, end_bp). Input: protein_label (HGNC or UniProt), ancestry, chromosome, start_bp, end_bp. Output: harmonised TSV slice + manifest + human-readable report.

Grade
C
Quality
74 / 100
Safety
Passed
GitHub stars
1,039

Unproven: rated by static analysis only, not yet compared head-to-head.

Our two independent classifiers differ on this skill's category, so treat the placement as provisional.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

View source on GitHubClawBio/ClawBio

Our review

Architecture
84 / 100
Maturity
Packaged: licensed, with a version or references
Security scan
Low-risk patterns
License
MIT
Adoption
Adopted by 0 other repositories, in 2 collections

What the scanner flagged

  • mentions secrets in text

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Scope (portable / vendor / repo-internal) not assessed; only the top of each category is read for scope
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

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