two-sample-mr-exposure-screening-reference-grounded

two-sample-mr-exposure-screening-reference-grounded is a Statistical modelling skill for AI agents, published by aipoch in the medical-research-skills repository on GitHub. Skillspace rates two-sample-mr-exposure-screening-reference-grounded C (77/100) and it passed the safety scan; the rating is based on static analysis only.

Generates complete two-sample Mendelian randomization research designs from a user-provided outcome, exposure or exposure family, and robustness direction. Use when a study centers on summary-statistics causal inference with instrument selection, harmonization, IVW-primary estimation, complementary estimators, sensitivity analyses, optional multivariable upgrades, and conservative evidence interpretation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

Grade
C
Quality
77 / 100
Safety
Passed
GitHub stars
1,449

Unproven: rated by static analysis only, not yet compared head-to-head.

Our two independent classifiers differ on this skill's category, so treat the placement as provisional.

This rating describes the version of the repository we crawled; it may have changed since, so go by its current files.

Our review

Architecture
94 / 100
Maturity
Packaged: licensed, with a version or references
Security scan
No issues found
License
MIT
Adoption
Adopted by 0 other repositories, in 2 collections
Scope
Portable: works in any project. General Mendelian randomization study design methodology

Not checked yet

  • Not judged on the rubric yet (not a contender in its category)
  • No blind task eval yet
  • Sibling files (scripts, references) not fetched; security scan covers SKILL.md only

Skillspace indexes and rates this skill; it does not host or endorse it. Run third-party skills at your own risk.